Paterson, A, St. John-Campbell , S, Mahon, M, Press, NJ & Frost, C 2015,
‘Catalytic meta-selective C–H functionalization to construct quaternary carbon centres’ <em>Chemical Communications</em>, vol 51, no. 64, pp. 12807-12810.
Abstract
A ruthenium catalyzed meta-selective C–H functionalization of 2-phenylpyridines with tertiary halides is described to establish challenging quaternary carbon centres in a regioselective manner. Preliminary studies suggest the C–H functionalization proceeds through a radical process directed via a remote σ-activation.
